Jared Padalecki made a lot of his fans worried after he posted a cryptic message on Twitter. Sadly, he was not able to attend the JIBCON 2015 due to his personal issue.

"Dear #JIBCON and #AHBL6, I am in desperate and urgent need of my family," the "Supernatural" star wrote. "I am so sorry to tell you this, but I must head home. I need all the love I can get right now. Please, please give me a few seconds of your time and write me. #AlwaysKeepFighting"

His fans and following were quick to give their support via social media.

"You are our anchor in many situations," wrote one fan. "Let us be yours. You are not alone!"

"Beloved @jarpad, I do not know what happened," wrote another. "But I know your heart. I speak for man when I say it kills me to think of you hurting."

Padalecki has touched a lot of hearts and helped a lot of people with his T-shirt campaign, "Always Keep Fighting." The proceeds of his heartfelt move will be benefiting the nonprofit organization, To Write Love on Her Arms. This group aims to assist people who are struggling with self-injury, addiction, depression, and suicide.

Padalecki, himself, had previously opened up about his past struggles with depression, according to Variety.

His "Supernatural" co-star sent his love as well. "Get some rest, my brother," Jensen Ackles wrote. "I got your back. Always."

Even "Arrow" star Stephen Amell, who is a good friend of the two on-screen Winchester brothers, also showed his support. "Hey, @jarpad," he wrote. "I got you."

It was during the JIBCON opening that Ackles revealed why his partner had to skip the event. "In true Jared fashion, he exhausted himself to the point where he had to tap out," he explained, according to Hollywood Life. "He needed to go home and get some rest and be with his family. He knows that THIS family is going to miss him."

"He is a big guy with a big heart and sometimes he just does not know when to stop giving himself," Ackles added.

Padalecki's manager also gave an explanation to the actor’s worried fans.

"Jared wanted everyone to know he loves meeting his fans around the world and was very upset at having to cancel his trips to Rome and Australia," Padalecki's manager said in a statement via E! Online.

"Jared pushed himself to his limits and is suffering from exhaustion," the statement continued. "His SPN family is so important to him and he asks that they 'Always Keep Fighting.'"

Despite this obstacle, Padalecki's manager revealed that the actor is looking forward to shooting the 11th season of "Supernatural" in July.